CHARMD
Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database
English (en)
Français (fr)
Español (es)
CNR Website
Home
Login
Data
All data
Antivirals
Bibliography
Therapeutic targets
Tools
Search
Submit mutations
Request expertise
Genotyping tool
Gene maps
Contact
Notice
How to cite
Last update : Mon 20 Apr 2026
TOP
Measure details
Mutant:
L776M
Gene:
UL54
Virus:
Human betaherpesvirus 5
Strain:
Reference:
Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation. (May 2008)
Antiviral:
Ganciclovir
EC50 ratio: 2.50
Phenotype: Low level resistance
Passage: N/A
Source: N/A
Marker: Recombinant
Details:
PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer
Observations:
Autre publi ID : 24903568 Mutation fr?quemment retrouv?e chez les patients re?evant des CS h?matopo?etiques
Tilloy
et al.
, 2024
Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230