CHARMD

TOP

• Mutant: K513Q
• Gene: UL54
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Drug Resistance Assessed in a Phase 3 Clinical Trial of Maribavir Therapy for Refractory or Resistant Cytomegalovirus Infection in Transplant Recipients. (Feb 2024)


• Antiviral: Ganciclovir
• EC50 ratio: 6.60
• Phenotype: High level resistance
• Passage: N/A
• Source: N/A
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • No observations associated