CHARMD

TOP

• Mutant: K513N
• Gene: UL54
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture. (Sep 1998)


• Antiviral: Foscarnet
• EC50 ratio: 1.50
• Phenotype: No resistance
• Passage: N/A
• Source: N/A
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID : 24903568