CHARMD

TOP

• Mutant: D413E
• Gene: UL54
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus. (Jul 2003)


• Antiviral: Cidofovir
• EC50 ratio: 4.30
• Phenotype: Intermediate level resistance
• Passage: N/A
• Source: N/A
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID : 24903568 20961907 9129071