CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    Conserved domains and structure prediction of human cytomegalovirus UL27 protein.

    Mutations:

    Mutant Gene Virus Antiviral EC50 ratio Phenotype
    P10L UL27 Human betaherpesvirus 5 Natural polymorphism
    L11P UL27 Human betaherpesvirus 5 Natural polymorphism
    P12L UL27 Human betaherpesvirus 5 Natural polymorphism
    A58T UL27 Human betaherpesvirus 5 Natural polymorphism
    D81N UL27 Human betaherpesvirus 5 Natural polymorphism
    A83V UL27 Human betaherpesvirus 5 Natural polymorphism
    A84P UL27 Human betaherpesvirus 5 Natural polymorphism
    A84V UL27 Human betaherpesvirus 5 Natural polymorphism
    K90R UL27 Human betaherpesvirus 5 Natural polymorphism
    H97R UL27 Human betaherpesvirus 5 Natural polymorphism
    L133I UL27 Human betaherpesvirus 5 Natural polymorphism
    A134T UL27 Human betaherpesvirus 5 Natural polymorphism
    E229D UL27 Human betaherpesvirus 5 Natural polymorphism
    N289D UL27 Human betaherpesvirus 5 Natural polymorphism
    D294N UL27 Human betaherpesvirus 5 Natural polymorphism
    D294G UL27 Human betaherpesvirus 5 Natural polymorphism
    H297Y UL27 Human betaherpesvirus 5 Natural polymorphism
    D298G UL27 Human betaherpesvirus 5 Natural polymorphism
    N300G UL27 Human betaherpesvirus 5 Natural polymorphism
    P307L UL27 Human betaherpesvirus 5 Natural polymorphism
    V310A UL27 Human betaherpesvirus 5 Natural polymorphism
    H313Y UL27 Human betaherpesvirus 5 Natural polymorphism
    D351N UL27 Human betaherpesvirus 5 Natural polymorphism
    S363W UL27 Human betaherpesvirus 5 Natural polymorphism
    I367V UL27 Human betaherpesvirus 5 Natural polymorphism
    G421E UL27 Human betaherpesvirus 5 Natural polymorphism
    R465C UL27 Human betaherpesvirus 5 Natural polymorphism
    T519A UL27 Human betaherpesvirus 5 Natural polymorphism
    A520V UL27 Human betaherpesvirus 5 Natural polymorphism
    R531Q UL27 Human betaherpesvirus 5 Natural polymorphism
    H557Q UL27 Human betaherpesvirus 5 Natural polymorphism
    A558V UL27 Human betaherpesvirus 5 Natural polymorphism
    A565T UL27 Human betaherpesvirus 5 Natural polymorphism
    P571T UL27 Human betaherpesvirus 5 Natural polymorphism
    H606Y UL27 Human betaherpesvirus 5 Natural polymorphism


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230