Table 5. Structure-activity relationships.
The table gives the regression coefficients (with their standard deviation in parentheses).
c is the constant term, r2 the coefficient of determination, s the residual standard deviation and F the variance ratio.
| Explained variable |
MLP+ |
Vmc |
 |
Vx |
 |
c |
r2 |
s |
F |
| pC50 (A) |
0.22 (0.04) |
0.77 (0.17) |
-17.7 (7.9) |
|
|
3.21 (1.33) |
0.9 |
0.21 |
23.3 |
| pC50 (B) |
0.25 (0.05) |
0.77 (0.20) |
-17.1 (9.6) |
|
|
3.03 (1.61) |
0.87 |
0.25 |
18.0 |
| pC50 (A) |
0.20 (0.05) |
|
|
1.04 (0.24) |
|
0.22 (0.22) |
0.81 |
0.27 |
18.9 |
| pC50 (B) |
0.24 (0.06) |
|
|
1.03 (0.26) |
|
0.15 (0.24) |
0.79 |
0.30 |
17.4 |
| pC50 (A) |
0.21 (0.06) |
|
|
|
0.94 (0.25) |
0.29 (0.23) |
0.77 |
0.29 |
15.2 |
| pC50 (B) |
0.25 (0.06) |
|
|
|
0.94 (0.26) |
0.27 (0.24) |
0.77 |
0.32 |
15.0 |