{"id":2975,"date":"2025-11-12T00:00:00","date_gmt":"2024-07-04T00:00:00","guid":{"rendered":"https:\/\/www.unilim.fr\/p-and-t\/?page_id=2975"},"modified":"2025-11-14T08:39:36","modified_gmt":"2025-11-14T07:39:36","slug":"clinical-research","status":"publish","type":"page","link":"https:\/\/www.unilim.fr\/p-and-t\/en\/research\/clinical-research\/","title":{"rendered":"Clinical Research"},"content":{"rendered":"
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The Clinical Research Unit in Pharmacology and Toxicology (RCPT), located within the Department of Pharmacology, Toxicology, and Pharmacovigilance at the University Hospital of Limoges (CHU de Limoges), serves as a support structure for UMR-1248 Pharmacology & Transplantation.<\/p>\n

It coordinates clinical studies<\/strong> sponsored by CHU de Limoges and INSERM, working closely with other units within the department (Biological Pharmacology and Pharmacokinetics, Pharmacometrics and Artificial Intelligence, and Environmental Toxicology and Occupational Health) as well as clinical departments involved in the projects (notably Nephrology, Dialysis and Transplantation, and Hepato-Gastroenterology and Nutrition). These studies primarily focus on immunosuppressive drugs, used in transplantation as well as in other conditions such as autoimmune diseases and cancer.<\/p>\n <\/div>\n <\/div>\n

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Caroline Monchaud<\/h4>\n

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The RCPT Clinical Research Unit supports members of UMR1248 in designing clinical research projects<\/strong>, collaborating with the sponsor throughout the entire process\u2014from the initial research idea to its valorization<\/strong>. This includes: search for funding, literature review, formulating research hypotheses, regulatory compliance, drafting clinical research protocols, coordinating participating centers, managing biological samples, conducting pharmacology and toxicology analyses, data management, statistical analyses and pharmacokinetic modeling, preparing final study reports, presenting findings at conferences and publishing in scientific journals.
\nThe RCPT Unit constitutes and manages biological collections<\/strong> related to the research themes of UMR1248. It is a member of CRBioLim (Biological Resource Center of CHU Limoges) and is responsible for storing biological resources (biological samples and associated data recorded in specialized software) in accordance with current standards. Its key focus areas include: \u201cbiomarkers in transplantation\u201d, \u201cautoimmune diseases\u201d, \u201concology biomarkers\u201d and \u201cbiomarkers of response to anti-infective treatments\u201d.
\nThe RCPT Unit\u2019s activities comply with Good Clinical Practices<\/strong> (GCP) and current regulations. Additionally, it collaborates closely with INSERM UMR1248 research and CRBioLim operations for biological sample management.<\/p>\n

Consequently, RCPT\u2019s activities align with the laboratory\u2019s quality systems, which are accredited under the ISO 15189<\/strong> medical biology standard and certified under the ISO 20387<\/strong> biobank standard (CRBioLim).<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n

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\n Some examples <\/h4>\n <\/div>\n
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