1 September 2021
Clinical Pharmacology & Therapeutics Journal highlights two major articles about Machine Learning in Pharmacology
The relevance of machine learning techniques in pharmacology and in drug monitoring is “honoured” in 110th Volume, Issue 2 of [...]
12 January 2021
Tacrolimus exposure prediction using machine learning
The aim of this work is to estimate the area‐under the blood concentration curve of tacrolimus following twice‐a‐day (BID) or once‐a‐day [...]
12 August 2020
Review: Effects of Ischemia-Reperfusion on Tubular Cell Membrane Transporters and Consequences in Kidney Transplantation
Ischemia-reperfusion (IR)-induced acute kidney injury (IRI) is an inevitable event in kidney transplantation. It is a complex [...]
15 May 2018
Review: Pharmacokinetic models to assist the prescriber in choosing the best tacrolimus dose
Due to a high inter-individual variability in its pharmacokinetics, tacrolimus dose individualization is mandatory. Even though the expert [...]
11 May 2018
First structural elucidation of the human ABCC4/MRP4 exporter in lipid bilayers
The ABCC4/MRP4 exporter has a clinical impact on membrane transport of a broad range of xenobiotics. It is expressed at key locations for [...]