François-Ludovic SAUVAGE obtained a diploma of Chemical Engineer and a Master degree in Analytical Chemistry at the Ecole Nationale Supérieure de Chimie of Mulhouse (France). He held the position of Chemical Engineer in the department of Pharmacology and Toxicology of Limoges University Hospital (France) and is a member of the INSERM unit since its creation in 2007. He has been nominated as Research Engineer Inserm in January 2015. His current research activity focuses on the development of analytical methods developed in the INSERM unit and particularly in peptidomics and proteomics as part of the European program Biomargin of which he was a member. François-Ludovic has written and contributed to several peer-reviewed publications. His principal publications are:

 

Sauvage FL, Gaulier JM, Lachâtre G, Marquet P. A fully automated turbulent-flow liquid chromatography-tandem mass spectrometry technique for monitoring antidepressants in human serum. Ther Drug Monit. 2006; 28(1):123-30. (IF 3,032)

Sauvage FL, Saint-Marcoux F, Duretz B, Deporte D, Lachâtre G, Marquet P. Screening of drugs and toxic compounds with liquid chromatography-linear ion trap tandem mass spectrometry. Clin Chem. 2006; 52(9):1735-42. (IF 5,454)

Saint-Marcoux F, Sauvage FL, Marquet P. Current role of LC-MS in therapeutic drug monitoring. Anal Bioanal Chem. 2007; 388(7):1327-49. (IF 2,867)

Loustaud-Ratti V, Alain S, Rousseau A, Hubert IF, Sauvage FL, Marquet P, Denis F, Lunel F, Calès P, Lefebvre A, Fauchais AL, Liozon E, Vidal E. Ribavirin exposure after the first dose is predictive of sustained virological response in chronic hepatitis C. Hepatology. 2008; 47(5):1453-61. (IF 10,734)

Sauvage FL, Gaulier JM, Lachâtre G, Marquet P. Pitfalls and prevention strategies for liquid chromatography-tandem mass spectrometry in the selected reaction-monitoring mode for drug analysis. Clin Chem. 2008; 54(9):1519-27. (IF 4,803)

Lamoureux F, Gaulier JM, Sauvage FL, Mercerolle M, Vallejo C, Lachâtre G. Determination of ethyl-glucuronide in hair for heavy drinking detection using liquid chromatography-tandem mass spectrometry following solid-phase extraction. Anal Bioanal Chem. 2009; 394(7):1895-901. (IF 3,328)

Sauvage FL, Picard N, Saint-Marcoux F, Gaulier JM, Lachâtre G, Marquet P. General unknown screening procedure for the characterization of human drug metabolites in forensic toxicology: applications and constraints. J Sep Sci. 2009; 32(18):3074-83. (IF 2,746)

Lamoureux F, Mestre E, Essig M, Sauvage FL, Marquet P, Gastinel LN. Quantitative proteomic analysis of cyclosporine-induced toxicity in a human kidney cell line and comparison with tacrolimus. J Proteomics. 2011; 75(2):677-94. (IF 4,878)

Al Saabi A, Allorge D, Sauvage FL, Tournel G, Gaulier JM, Marquet P, Picard N. Involvement of UDP-glucuronosyltransferases UGT1A9 and UGT2B7 in ethanol glucuronidation, and interactions with common drugs of abuse. Drug Metab Dispos. 2013; 41(3):568-74.

Billat PA, Sauvage FL, Picard N, Tafzi N, Alain S, Essig M, Marquet P, Saint-Marcoux F. Liquid chromatography tandem mass spectrometry quantitation of intracellular concentrations of ganciclovir and its phosphorylated forms. Anal Bioanal Chem. 2015 May;407(12):3449-56.