CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    R369K

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Letermovir 4.90 Intermediate level resistance Clinical Isolate Details Relative frequency of cytomegalovirus UL56 gene mutations detected in genotypic letermovir resistance testing. (Nov 2022)

    Mutations at the same locus:

    Mutant Resistances
    R369G Letermovir: High level resistance
    R369M Letermovir: High level resistance
    R369S Letermovir: High level resistance
    R369T Letermovir: High level resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230