CHARMD
Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database
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Last update : Mon 20 Apr 2026
TOP
K350R
Virus:
Human betaherpesvirus 5
Gene:
UL56
Resistance summary:*
Letermovir:
No resistance
*If there is more than one line per antiviral, please refer to the table below
Antiviral assays:
Antiviral
EC50 ratio
Phenotype
Strain
Source
Marker
Assay
Reference
Letermovir
1.10
No resistance
Clinical Isolate
Details
Relative frequency of cytomegalovirus UL56 gene mutations detected in genotypic letermovir resistance testing. (Nov 2022)
Tilloy
et al.
, 2024
Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230