CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    F261L

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Letermovir 2.80 Low level resistance Laboratory strain Recombinant Details Rapid In Vitro Evolution of Human Cytomegalovirus UL56 Mutations That Confer Letermovir Resistance. (Oct 2015)

    Mutations at the same locus:

    Mutant Resistances
    F261C Letermovir: Intermediate level resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230