| Antiviral | EC50 ratio | Phenotype | Strain | Source | Marker | Assay | Reference |
|---|---|---|---|---|---|---|---|
| Letermovir | 5.00 | High level resistance | Laboratory strain | Recombinant | Details | Geno- and phenotypic characterization of human cytomegalovirus mutants selected in vitro after letermovir (AIC246) exposure. ( 2014) | |
| Letermovir | 8.90 | High level resistance | Laboratory strain, Clinical Isolate | Details | Relative frequency of cytomegalovirus UL56 gene mutations detected in genotypic letermovir resistance testing. (Nov 2022) | ||
| Letermovir | 8.10 | High level resistance | Laboratory strain, Clinical Isolate | Details | Phenotypes of cytomegalovirus genetic variants encountered in a letermovir clinical trial illustrate the importance of genotyping validation. (Aug 2024) |
| Mutant | Resistances |
|---|---|
| V231A |
Letermovir:
|