CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database

S229F

Virus: Human betaherpesvirus 5
Gene: UL56
Resistance summary:*
- Letermovir: No resistance

*If there is more than one line per antiviral, please refer to the table below

Antiviral assays:

Antiviral	EC50 ratio	Phenotype	Strain	Source	Marker	Assay	Reference
Letermovir	1.80	No resistance		Laboratory strain	Recombinant	Details	A third component of the human cytomegalovirus terminase complex is involved in letermovir resistance. (Dec 2017)

Tilloy et al., 2024

Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230