CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    591-607del

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 6.20 High level resistance Laboratory strain, Clinical Isolate Recombinant Details Cytomegalovirus UL97 phosphotransferase mutations that affect susceptibility to ganciclovir. (Jan 2002)

    Mutations at the same locus:

    Mutant Resistances
    591-594del Ganciclovir: High level resistance
    A591D Ganciclovir:
    A591V Ganciclovir: No resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230