Herpesvirus Antiviral Resistance
Database


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    H411N

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Maribavir 9.00 High level resistance Laboratory strain Recombinant Details Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant. (Jan 2008)
    Ganciclovir 0.71 No resistance Laboratory strain Recombinant Details Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant. (Jan 2008)

    Mutations at the same locus:

    Mutant Resistances
    H411L Maribavir: Range of values of High level resistance
    H411L Ganciclovir: No resistance
    H411Y Maribavir: High level resistance
    H411Y Ganciclovir: No resistance