CHARMD
Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database
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Last update : Mon 20 Apr 2026
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Measure details
Mutant:
C25F
Gene:
UL56
Virus:
Human betaherpesvirus 5
Strain:
Reference:
New Locus of Drug Resistance in the Human Cytomegalovirus UL56 Gene Revealed by In Vitro Exposure to Letermovir and Ganciclovir. (Sep 2018)
Antiviral:
Letermovir
EC50 ratio: 5.40
Phenotype: High level resistance
Passage: N/A
Source: Laboratory strain
Marker: Recombinant
Details:
SEAP
Observations:
No observations associated
Tilloy
et al.
, 2024
Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230