CHARMD

TOP

• Mutant: C603W
• Gene: UL97
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Ganciclovir and maribavir cross-resistance revisited: Relative drug susceptibilities of canonical cytomegalovirus mutants. (Feb 2024)


• Antiviral: Ganciclovir
• EC50 ratio: 5.90
• Phenotype: High level resistance
• Passage: N/A
• Source: Laboratory strain, Clinical Isolate
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID : update 202419207351, 9063923 24903568 15230476 11807689 20385869 12198609 11595579 11050017 23985916 11740736 20961907 11704031 9291334 12508158 31940472 Mutation fr?quemment retrouv?e chez les patients re?evant des CS h?matopo?etiques