CHARMD

TOP

• Mutant: A594V
• Gene: UL97
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Ganciclovir and maribavir cross-resistance revisited: Relative drug susceptibilities of canonical cytomegalovirus mutants. (Feb 2024)


• Antiviral: Ganciclovir
• EC50 ratio: 6.90
• Phenotype: High level resistance
• Passage: N/A
• Source: Laboratory strain, Clinical Isolate
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID : update 2024 7814623, 19063923 24991428 24903568 15230476 11807689 20385869 9207351 10443790 11050017 23985916 15258973 15980340 9129070 10968438 15634973 23375740 23668613 26098499 25130511 31940472 Mutation fr?quemment retrouv?e chez les patients re?evant des CS h?matopo?etiques