CHARMD
Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database
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Last update : Mon 20 Apr 2026
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Measure details
Mutant:
P521L
Gene:
UL97
Virus:
Human betaherpesvirus 5
Strain:
Reference:
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
Antiviral:
Maribavir
EC50 ratio: 428.00
Phenotype: High level resistance
Passage: N/A
Source: Laboratory strain, Clinical Isolate
Marker: Recombinant
Details:
SEAP
Observations:
IS50: >100 selon Chou 2020 : 31940472
Tilloy
et al.
, 2024
Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230