CHARMD

TOP

• Mutant: H520Q
• Gene: UL97
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Ganciclovir and maribavir cross-resistance revisited: Relative drug susceptibilities of canonical cytomegalovirus mutants. (Feb 2024)


• Antiviral: Ganciclovir
• EC50 ratio: 9.70
• Phenotype: High level resistance
• Passage: N/A
• Source: Laboratory strain, Clinical Isolate
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • updated 2024, Autre publi ID : 9129070, 24903568 11807689 12198609 23985916 11740736 11704031 16000504 31940472 Mutation fr?quemment retrouv?e chez les patients re?evant des CS h?matopo?etiques