CHARMD

TOP

• Mutant: V946L
• Gene: UL54
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet. (Sep 2011)


• Antiviral: Ganciclovir
• EC50 ratio: 1.10
• Phenotype: No resistance
• Passage: N/A
• Source: N/A
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID : 22001948