CHARMD

TOP

• Mutant: E756K
• Gene: UL54
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus. (Jul 2003)


• Antiviral: Foscarnet
• EC50 ratio: >8.00
• Phenotype: At least High level resistance
• Passage: N/A
• Source: N/A
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID : 25143583 24621186 11595579 Mutation fr?quemment retrouv?e chez les patients re?evant des CS h?matopo?etiques