CHARMD

TOP

• Mutant: Q578H
• Gene: UL54
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Phenotypic diversity of cytomegalovirus DNA polymerase gene variants observed after antiviral therapy. (Apr 2011)


• Antiviral: Foscarnet
• EC50 ratio: 4.50
• Phenotype: Intermediate level resistance
• Passage: N/A
• Source: N/A
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID : 12637079 22001948 24903568 24183928 24890586 Mutation fr?quemment retrouv?e chez les patients re?evant des CS h?matopo?etiques