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PUBLICATIONS UMR CNRS 6101

P3. Delpy L, Le Bert M, Cogné M, Khamlichi AA, 2003, Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes,

Eur J Immunol., 33(8):2108-13.

P4. Denizot Y, Gainant A, Guglielmi L, Bouvier S, Cubertafond P, Mathonnet M, 2003, Tissue concentrations of platelet-activating factor in colorectal carcinoma: inverse relationships with Dukes' stage of patients,

Oncogene, 22(46):7222-4.

P5. Denizot Y, Guglielmi L, Cornu E, Nathan N, 2003, Alterations in plasma angiogenic growth factor concentrations after coronary artery bypass graft surgery: relationships with post-operative complications,

Cytokine, 24(1-2):7-12.

P6. Denizot Y, Guglielmi L, Donnard M, Trimoreau F, 2003, Platelet-activating factor and normal or leukaemic haematopoiesis,

Leuk Lymphoma, 44(5):775-82.

P7. Denizot Y, Liozon E, Guglielmi L, Ly K, Soria P, Loustaud V, Vidal E, Jauberteau MO, 2003, No evidence for a putative involvement of platelet-activating factor in systemic lupus erythematosus without active nephritis,

Mediators Inflamm., 12(2):101-5.

P8. Guglielmi L, Le Bert M, Cogné M, Denizot Y, 2003, Effect of the Emu IgH enhancer on expression of a GFP reporter gene in transfected B cells and transgenic mice,

Immunol Lett., 86(1):77-83.

P9. Guglielmi L, Le Bert M, Comte I, Dessain ML, Drouet M, Ayer-Le Lievre C, Cogné M, Denizot Y, 2003, Combination of 3' and 5' IgH regulatory elements mimics the B-specific endogenous expression pattern of IgH genes from pro-B cells to mature B cells in a transgenic mouse model,

Biochim Biophys Acta., 1642(3):181-90.

P10. Guglielmi L, Le Bert M, Truffinet V, Cogné M, Denizot Y, 2003, Insulators to improve expression of a 3'IgH LCR-driven reporter gene in transgenic mouse models,

Biochem Biophys Res Commun., Vol 307(3):466-71.

P11. Guglielmi L, Trimoreau F, Donnard M, Jaccard A, Bordessoule D, Denizot Y, 2003, Presence of membrane platelet-activating factor receptors on B cells of chronic B cell leukaemia patients,

Leuk Lymphoma., 44(6):1087-8.

P12. Guglielmi L, Truffinet V, Cogné M, Denizot Y, 2003, The beta-globin HS4 insulator confers copy-number dependent expression of IgH regulatory elements in stable B cell transfectants,

Immunol Lett., Vol 89(2-3):119-23.

P13. Morvan CL, Pinaud E, Decourt C, Cuvillier A, Cogné M, 2003, The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation,

Blood, 102(4):1421-7.

P14. Trimoreau F, Donnard M, Turlure P, Gachard N, Bordessoule D, Feuillard J. The CD4+ CD56+ CD116- CD123+ CD45RA+ CD45RO- profile is specific of DC2 malignancies.

Haematologica. 2003 Mar; 88(3).

P15. Touitou R, Arbach H, Cochet C, Feuillard J, Martin A, Raphael M, Joab I. Heterogeneous Epstein-Barr virus latent gene expression in AIDS-associated lymphomas and in type I Burkitt's lymphoma cell lines.

J Gen Virol. 2003 Apr; 84(Pt 4):949-57.

P16. Bene MC, Feuillard J, Jacob MC; Groupe d'Etude Immunologique des Leucemies.  Plasmacytoid dendritic cells: from the plasmacytoid T-cell to type 2 dendritic cells CD4+CD56+ malignancies.

         Semin Hematol. 2003 Jul; 40(3):257-66.

P17. Jacob MC, Chaperot L, Mossuz P, Feuillard J, Valensi F, Leroux D, Bene MC, Bensa JC, Briere F, Plumas J. CD4+ CD56+ lineage negative malignancies: a new entity developed from malignant early plasmacytoid dendritic cells.

Haematologica. 2003 Aug; 88(8):941-55.

P18. Boya P, Morales MC, Gonzalez-Polo RA, Andreau K, Gourdier I, Perfettini JL, Larochette N, Deniaud A, Baran-Marszak F, Fagard R, Feuillard J, Asumendi A, Raphael M, Pau B, Brenner C, Kroemer G. The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family.

Oncogene. 2003 Sep 18; 22(40):6220-30.

P19. Le Guern V, Le Roux G, Martin A, Feuillard J, Cohen P, Poirel H, Raphael M, Guillevin L, Mouthon L. Lymphoma complicating common variable immunodeficiency with granulomatousdisease: report of two cases.

Eur J Haematol. 2003 Dec; 71(6):459-63.

2004:

P20. Decourt C, Galea HR, Sirac C, Cogné M, 2004, Immunologic basis for the rare occurrence of true nonsecretory plasma cell dyscrasias,

J Leuk Biol., 76(3):528-36.

P21. Delpy L, Sirac C, Le Morvan C, Cogné M, 2004, Somatic hypermutation witnesses allelic inclusion at the transcriptional level for non-functionally rearranged IgH genes of mature B cells.

J. Immunol. 2004a 1;173:1842-8

P22. Delpy L, Sirac C, Magnoux E, Duchez S, Cogné M, RNA surveillance down-regulates expression of nonfunctional kappa alleles and detects premature termination within the last kappa exon,

Proc Natl Acad Sci U S A, 2004b, 101(19):7375-80.

P23. Denizot Y, Donnard M, Guglielmi L, Faucher JL, Jaccard A, Bordessoule D, Trimoreau F, Detection of functional platelet-activating factor receptors on leukemic B cells of chronic lymphocytic leukemic patients,

Leuk Lymphoma., 2004, 45(3):515-8.

P24. Denizot Y, Truffinet V, Bouvier S, Gainant A, Cubertafond P, Mathonnet M, 2004, Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer,

Mediators Inflamm. 2004, 13(1):53-4.

P25. Glaudet F, Denis V, Cogné M, Khamlichi AA, 2004, Induction of somatic hypermutation by antigen-specific B cell receptors in the human BL2 cell line,

Eur J Immunol., 34(6):1637-45.

P26. Guglielmi L, Battu S, Le Bert M, Faucher JL, Cardot PJ, Denizot Y, 2004, Mouse embryonic stem cell sorting for the generation of transgenic mice by sedimentation field-flow fractionation,

Anal Chem., 76(6):1580-5.

P27. Guglielmi L, Truffinet V, Magnoux E, Cogné M, Denizot Y, 2004, The polymorphism of the locus control region lying downstream the human IgH locus is restricted to hs1,2 but not to hs3 and hs4 enhancers,

Immunol Lett., Vol 94(1-2):77-81.

P28. Khamlichi AA, Glaudet F, Oruc Z, Denis V, Le Bert M, Cogné M, 2004, Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat,

Blood, 103(10):3828-36.

P29. Lecuit M, Abachin E, Martin A, Poyart C, Pochart P, Suarez F, Bengoufa D, Feuillard J, Lavergne A, Gordon JI, Berche P, Guillevin L, Lortholary O. Immunoproliferative small intestinal disease associated with Campylobacter jejuni.

N Engl J Med. 2004 Jan 15; 350(3):239-48.

P30. Duval A, Raphael M, Brennetot C, Poirel H, Buhard O, Aubry A, Martin A, Krimi A, Leblond V, Gabarre J, Davi F, Charlotte F, Berger F, Gaidano G, Capello D, Canioni D, Bordessoule D, Feuillard J, Gaulard P, Delfau MH, Ferlicot S, Eclache V, Prevot S, Guettier C, Lefevre PC, Adotti F, Hamelin R. The mutator pathway is a feature of immunodeficiency-related lymphomas.

Proc Natl Acad Sci U S A. 2004 Apr 6; 101(14):5002-7

P31. Baran-Marszak F, Feuillard J*, Najjar I, Le Clorennec C, Bechet JM, Dusanter-Fourt I, Bornkamm GW, Raphael M, Fagard R.  Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells.

         Blood. 2004 Oct 15; 104(8):2475-83.

2005 :

P32. Bridoux F, Sirac C, Hugue V, Decourt C, Thierry A, Quellard N, Abou-Ayache R, Goujon JM, Cogné M, Touchard G, 2005, Fanconi's syndrome induced by a monoclonal Vkappa3 light chain in Waldenstrom's macroglobulinemia,

Am J Kidney Dis, 45(4):749-57

P33. Denizot Y, Chianea T, Labrousse F, Truffinet V, Delage M, Mathonnet M, 2005, Platelet-activating factor and human thyroid cancer,

Eur J Endocrinol., 153(1):31-40.

P34. Denizot Y, Descottes B, Truffinet V, Valleix D, Labrousse F, Mathonnet M, 2005, Platelet-activating factor and liver metastasis of colorectal cancer,

Int J Cancer., 113(3):503-5.

P35. Denizot Y, Donnard M, Truffinet V, Malissein E, Faucher JL, Turlure P, Bordessoule D, Trimoreau F, 2005, Functional EP2 receptors on blast cells of patients with acute leukaemia,

Int J Cancer, 115(3):499-501.

P36. Denizot Y, Donnard M, Truffinet V, Turlure P, Faucher JL, Bordessoule D, Trimoreau F, 2005, Platelet-activating factor does not stimulate cAMP formation from immature forms of freshly isolated leukaemic blasts,

Leuk Lymphoma, 46(1):129-31.

P37. Guglielmi L, Truffinet V, Carrion C, Le Bert M, Cogné N, Cogné M, Denizot Y, 2005, The 5'HS4 insulator element is an efficient tool to analyse the transient expression of an Eµ-GFP vector in a transgenic mouse model,

Transgenic Res., Vol 14(4):361-4.

P38. Petit B, Chaury MP, Le Clorennec C, Jaccard A, Gachard N, Moalic-Judge S, Labrousse F, Cogné M, Bordessoule D, Feuillard J, 2005, Indolent lymphoplasmacytic and marginal zone B-cell lymphomas: absence of both IRF4 and Ki67 expression identifies a better prognosis subgroup,

Haematologica, 90(2):200-6.

P39.Reynaud S, Delpy L, Fleury L, Dougier HL, Sirac C, Cogné M, 2005, Interallelic class switch recombination contributes significantly to class switching in mouse B cells,

J Immunol. 174(10):6176-83.

P40. Truffinet V, Guglielmi L, Cogné M, Denizot Y, 2005, The chicken beta-globin HS4 insulator is not a silver bullet to obtain copy-number dependent expression of transgenes in stable B cell transfectants,

Immunol Lett., Vol 31;96(2):303-4.3

P41. Najjar I, Baran-Marszak F, Le Clorennec C, Laguillier C, Schischmanoff O, Youlyouz-Marfak I, Schlee M, Bornkamm GW, Raphael M, Feuillard J, Fagard R. Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells.

         J Virol. 2005 Apr; 79(8):4936-43.

P42. Gonzalez-Polo RA, Carvalho G, Braun T, Decaudin D, Fabre C, Larochette N, Perfettini JL, Djavaheri-Mergny M, Youlyouz-Marfak I, Codogno P, Raphael M, Feuillard J, Kroemer G. PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor.

Oncogene. 2005 Aug 8 ; [Epub ahead of print]

P43. Bornkamm GW, Berens C, Kuklik-Roos C, Bechet JM, Laux G, Bachl J, Korndoerfer M, Schlee M, Holzel M, Malamoussi A, Chapman RD, Nimmerjahn F, Mautner J, Hillen W, Bujard H, Feuillard J. Stringent doxycycline-dependent control of gene activities using an episomal one-vector system.

Nucleic Acids Res. 2005 Sep 7; 33(16)

2006 :

P45. Goormachtigh G, Ouk TS, Mougel A, Tranchand-Bunel D, Masy E, Le Clorennec C, Feuillard J, Bornkamm GW, Auriault C, Manet E, Fafeur V, Adriaenssens E, Coll J. Autoactivation of the Epstein-Barr virus oncogenic protein LMP1 during type II latency through opposite roles of the NF-kappaB and JNK signaling pathways.

J Virol. 2006 Aug;80(15):7382-93.

P46. Baran-Marszak F, Laguillier C, Youlyouz I, Feuillard J, Mariette X, Fagard R, Raphael M. Effect of tumor necrosis factor alpha and infliximab on apoptosis of B lymphocytes infected or not with Epstein-Barr virus.

Cytokine. 2006 Mar 21;33(6):337-45.

P47. Le Clorennec C, Youlyouz-Marfak I, Adriaenssens E, Coll J, Bornkamm GW, Feuillard J, EBV latency III immortalization program sensitizes B cells to induction of CD95-mediated apoptosis via LMP1: role of NF-{kappa}B, STAT1, and p53,

Blood, 2006, 107(5):2070-8.

P48. Malissein E, Reynaud S, Bordessoule D, Faucher JL, Turlure P, Trimoreau F, Denizot Y, 2006, PGE(2) receptor subtype functionality on immature forms of human leukemic blasts,

Leuk Res. 2006 Feb 3

P49. Reynaud S, Malissein E, Donnard M, Bordessoule D, Turlure P, Trimoreau F, Denizot Y. Functional platelet-activating factor receptors in immature forms of leukemic blasts.

Leuk Res. 2006 Jul 10;

P50. Mathonnet M, Descottes B, Valleix D, Labrousse F, Truffinet V, Denizot Y. Quantitative analysis using ELISA of vascular endothelial growth factor and basic fibroblast growth factor in human colorectal cancer, liver metastasis of colorectal cancer and hepatocellular carcinoma.

World J Gastroenterol. 2006 21;12:3782-3.

P51. Mathonnet M, Descottes B, Valleix D, Truffinet V, Labrousse F, Denizot Y. Platelet-activating factor in cirrhotic liver and hepatocellular carcinoma.

World J Gastroenterol. 2006 ;12 : 2773-8.

P52. Mathonnet M, Descottes B, Valleix D, Labrousse F, Denizot Y. VEGF in hepatocellular carcinoma and surrounding cirrhotic liver tissues.

World J Gastroenterol. 2006 ;12: 830-1.

P53. Samara M, Oruc Z, Dougier HL, Essawi T, Cogné M, Khamlichi AA, 2006, Germ line transcription in mice bearing neor gene downstream of Ig3 exon in the Ig heavy chain locus,

Int Immunol. 2006 Apr;18(4):581-589

P54. H-L Dougier, S Reynaud, C Carrion, E Pinaud, L Delpy and M Cogné Interallelic class switch recombination allows trans-complementation of an IgH locus switching defect.

Eur. J. Immunol 2006; 36:2181-2191

P55. C Sirac, F Bridoux, C Carrion, O Devuyst, B Fernandez, J-M Goujon, C El Hamel, J-C Aldigier, G Touchard, M Cogné Role of the monoclonal k chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi’s syndrome.

Blood 2006a; 108(2):536-43.

P56. Sirac C.*, Carrion C., Duchez S., Comte I. , and Cogné M. Light chain inclusion permits terminal B cell differentiation and does not necessarily promote autoreactivity.

Proc. Natl Acad. Sci. USA 2006b, 103:7747-52

P57. Boulanger E, Fuentes V, Meignin V, Mougenot B, Labaume S, Gouilleux-Gruart V, Cogne M, Aucouturier P, Clauvel JP, Ronco P, Lassoued K. Polyclonal IgG4 hypergammaglobulinemia associated with plasmacytic lymphadenopathy, anemia and nephropathy.

Ann Hematol. 2006 , 85: 833-840